Danogen-50

Uses
Danogen-50 (Danazol) is indicated for the treatment of pain and other symptoms caused by endometriosis. It is also used to treat benign fibrocystic breast disease and hereditary angioedema. The main ingredient in this medicine is a synthetic androgen which is quite similar to testosterone, and when taken, it reduces the levels of oestrogen in the body while also increasing the androgen levels. This may help to control the excess growth of endometriotic tissue (as this tissue growth is caused by hormonal disturbances).

It may even help to relieve pain and prevent a worsening of the condition. However, this medicine is usually only considered when other treatments have failed, due to the risk of masculinisation and other side effects. Other potential uses have been studied, such as its effects if used for thrombocytopenia in those suffering from myelodysplastic syndrome, ITP and menorrhagia. However, it is generally not prescribed for these conditions.

Dosage and Administration
Danogen-50 (Danazol) is used for different conditions, and patients should note that the required dosage regimen will be individualised by their doctor, with various factors being taken into consideration. This medicine comes as 50mg capsules, which are taken orally. The dosage for fibrocystic breast disease usually ranges from 50mg to 200mg taken twice per day. Treatment usually commences during menstruation. Patients may notice a reduction in pain and other symptoms after 1 to 3 months of treatment, and 4 to 6 months may be needed in order for nodules to disappear.

In the event of a recurrence of symptoms, the patient may be told to start treatment again. The dosage for endometriosis may be different, and patients treating this condition may also need to start treatment during a menstrual period. The actual dosage regimen required may differ from the examples here, and therefore patients should only take the medicine in accordance with the instructions their doctor gives them.

Side effects
Treatment with Danogen-50 (Danazol) has been associated with side effects, and a list of examples is given here:

• Acne
• Oily skin
• Abnormal hair growth
• A reduced breast size
• Changes in the pitch of voice

You are advised to notify your doctor of any side effects that occur during treatment. In rare cases, patients may experience severe reactions. You must immediately go to the hospital if you experience pain in the abdomen that persists, bloody stools, coughing up blood, problems related to vision, a rapid increase in weight or any other serious side effects.

Precautions
Although rare, there have been reports of this medicine causing serious blood clots or benign intracranial hypertension. Seek medical attention immediately if any symptoms of these conditions are noticed.

These capsules are not to be taken during pregnancy due to the risk of harm to the fetus. Patients are advised to use non-hormonal contraception during treatment so as to prevent pregnancy.

Seek immediate emergency medical attention if you suffer an allergic reaction. Symptoms to watch for, which may be indicative of a reaction, include skin rashes, hives, swelling of the face or limbs, trouble breathing, and trouble swallowing.

Always use Danogen-50 (Danazol) as you have been prescribed by your doctor. Never self-medicate or change your dosage without first consulting your doctor. The correct dosage can vary depending on your health, medical history, and the severity of the condition being treated.

This medication may not be safe for all patients. Before you begin using it always disclose the following to your doctor:

• If you are pregnant or breastfeeding.
• If you suffer from any allergies.
• If you suffer from any other health conditions or illnesses.
• If you are using any other medicine (including all non-prescription).
• If you are using any supplements, vitamins, or herbal products of any kind.