MESACOL 400

Uses
Mesacol (Mesalamine) is used as a treatment for active ulcerative colitis and to prevent the return of ulcerative colitis symptoms. Other uses include treating Crohn's disease. The active component in this medicine is known as an aminosalicylate and is derived from salicylic acid. When taken, it can help to lessen intestinal inflammation due to inhibition of lipoxygenase enzymes. This in turn leads to a reduced amount of inflammatory leukotrienes being produced. As a result of this, relief from the symptoms commonly associated with ulcerative colitis, including pain in the abdomen, bloody diarrhoea and intestinal ulceration may occur.

Dosage and Administration
Mesacol (Mesalamine) is supplied in tablets, each of which contains 400mg of the active ingredient. Patients will be provided with proper dosage instructions by their doctor, and it is essential that these are fully complied with. Some adult patients treating ulcerative colitis may be told by their doctor to take a dosage ranging from 400mg to 800mg taken 3 times per day. Those affected by Crohn's disease may be directed to take 800mg 3 times per day. The exact dosage required can vary for each individual, and it is essential to only take the amount of medicine that your doctor tells you to take.

Side effects
Adult patients who are being treated with Mesacol (Mesalamine) for ulcerative colitis, Crohn's disease or any other conditions may experience side effects, such as:

• Loose stools
• Feeling constipated
• Dizzy sensation
• Sore back or joints
• Discomfort affecting the stomach

Inform your doctor if any side effects occur during treatment. Patients should note that although it is considered to be an infrequent occurrence, there is still the possibility of serious side effects associated with this medicine. You must immediately see your doctor if you experience severe pain in the stomach, signs of fever, a noticeable decrease in urination or any other symptoms of a severe reaction.

Precautions
Before you can start treatment, it is necessary to inform your doctor if you have a history of liver disease, medical conditions affecting the kidneys or pyloric stenosis.

These tablets must be swallowed whole. Do not chew, crush or bite them.

Seek immediate emergency medical attention if you suffer an allergic reaction. Symptoms to watch for, which may be indicative of a reaction, include skin rashes, hives, swelling of the face or limbs, trouble breathing, and trouble swallowing.

Always use Mesacol (Mesalamine) as you have been prescribed by your doctor. Never self-medicate or change your dosage without first consulting your doctor. The correct dosage can vary depending on your health, medical history, and the severity of the condition being treated.

This medication may not be safe for all patients. Before you begin using it always disclose the following to your doctor:

• If you are pregnant or breastfeeding.
• If you suffer from any allergies.
• If you suffer from any other health conditions or illnesses.
• If you are using any other medicine (including all non-prescription).
• If you are using any supplements, vitamins, or herbal products of any kind.