Diovan (Valsartan) is a drug that belongs to the group of specific angiotensin II receptor antagonists and has a pronounced hypotensive effect. Diovan is used to treat both primary (essential) and secondary hypertension. Also used in the complex treatment of myocardial infarction and chronic heart failure.
Diovan (Valsartan) competitively and selectively blocks angiotensin II receptors (subtype AT1), which are responsible for the effects of angiotensin II and are located in the vessels, heart, kidneys, brain, lungs and adrenal cortex. Diovan (Valsartan) suppresses all the effects of angiotensin II mediated through AT1 receptors, including vasoconstriction.
Diovan (Valsartan) reduces myocardial hypertrophy in patients with arterial hypertension.
Always follow your doctor`s instructions when using Diovan (Valsartan) to get the safest and most effective results from treatment. The drug is intended for oral use. The recommended dose is 80 mg once a day daily, regardless of the race, age and gender of the patient. The antihypertensive effect is observed in the first 2 weeks of treatment, the maximum effect after 4 weeks. For those patients who cannot achieve an adequate therapeutic response, the daily dose of Diovan (Valsartan) can be increased to 320 mg or additional diuretics are prescribed.
The total duration of therapy should be selected individually by the doctor.
The use of Diovan (Valsartan) may cause side effects in some patients including:
dizziness insomnia headache hypotension abdominal pain diarrhea nausea rash itchingContact your doctor immediately if you experience any serious or worrying symptoms.
Given the mechanism of action of angiotensin II antagonists, the risk to the fetus cannot be ruled out. Diovan (Valsartan) should not be used during pregnancy, as well as in women planning a pregnancy. If pregnancy is detected during the treatment with Diovan (Valsartan), woman should stop taking the drug as soon as possible.
It is not known whether valsartan passes into human breast milk; therefore, Diovan (Valsartan) should not be used during breast-feeding.
Patients taking Diovan (Valsartan) should be careful when driving and operating machineries.