Main Use | Active Ingredient | Marketed Name |
Epilepsy and bipolar disorder | Lamotrigine | Lamitor DT |
Uses
Lamitor DT-100 (Lamotrigine) belongs to the category of anticonvulsants and is used to treat and prevent seizures in patients with epilepsy. Also, the drug is used to prevent mood disorders (depression, mania, hypomania, mixed episodes) in patients with bipolar disorder.
The drug stabilizes neuronal membranes by influencing the presynaptic potential-dependent Na + channels, inhibits the pathological release of glutamic acid (an amino acid that plays a key role in the development of epileptic seizures), and also inhibits glutamate-induced depolarization.
Dosage and Administration
Always follow your doctor`s instructions when using Lamitor DT-100 (Lamotrigine) to get the safest and most effective results from treatment. The dosage is prescribed by the doctor individually for each patient. It depends on age, weight, concomitant illness and the general condition of the patient. Treatment begins with the lowest dosage with gradual increase to the required dose under the supervision of a doctor. You cannot suddenly stop treatment with the drug. To stop treatment, the dose is gradually reduced according to the doctor`s recommendations. To restore the use of the drug after its cancellation is possible only after consulting a doctor.
Side effects
The use of Lamitor DT-100 (Lamotrigine) may cause side effects in some patients including:
Precautions
Reception during pregnancy is contraindicated, except in cases where the expected benefit to the mother outweighs the potential risk to the fetus. Due to the inhibitory effect of lamotrigine on dihydrofolate reductase, the development of fetal malformations is likely in the case of treatment of pregnant women, but the available data to determine the degree of safety of lamotrigine for pregnant women are insufficient.
According to preliminary data, lamotrigine penetrates into breast milk, the concentration in breast milk can be 40-60% of the concentration in the mother`s plasma. The few observations show that the concentration of the drug in the serum of infants whose mothers took the drug during the breastfeeding period reached therapeutic levels. It is necessary to correlate the potential benefits of breastfeeding and the potential risk of side effects in the baby.