Anabrez

Uses
Anabrez (Anastrozole) is an aromatase inhibitor which is indicated for the treatment of oestrogen receptor positive breast cancer, as well as metastatic breast cancer. It works by affecting oestrogen production and availability in the body. The active ingredient in this medicine blocks aromatase activity. This enzyme is responsible for producing oestrogen, which is achieved via the conversion of testosterone and androstenedione into the sex hormone oestrogen.

By functioning as an inhibitor of aromatase, this medicine helps to trigger an overall reduction in oestrogen levels. Some forms of breast cancer will grow with the help of oestrogen, due to the oestrogen acting on the breast cancer cells, thereby speeding up the growth of cancer.

Blocking oestrogen production helps affect the spread of cancer, and prevent its growth. It may also decrease the likelihood of the cancer returning. In some cases, doctors have treated patients for endometriosis with this medicine. Medical researchers have also studied it effects if used by men to treat gynaecomastia, hypogonadism and prostate problems. This may be related to it decreasing excess oestrogen.

Dosage and Administration
Anabrez (Anastrozole) is provided in tablet form, and the medicine content of each tablet is 1mg. Instructions relating to the correct dosage and duration of treatment will be decided upon by your doctor. Postmenopausal women who are affected by types of cancer which are responsive to treatment with this medicine and who are being given it as a first line treatment may be instructed to administer 1mg per day. The doctor will monitor the patient's condition, however treatment usually continues until progression of the tumour is noticeable.

Side effects
Taking Anabrez (Anastrozole) could result in side effects, such as:

• Bone pain
• Joint pain
• Hot flushing
• Thinner hair
• Soreness which affects the fingers

You must remain in regular contact with your doctor while taking this medicine and report any side effects that you notice. Some of the reactions that can occur as a result of taking this medicine can pose a serious threat to your health. You will need to be treated immediately if you notice limb inflammation, visual problems, serious headaches, blurry vision, ulcers on the skin or any other serious reactions that are not listed here.

Precautions
This medicine could contribute to osteoporosis or worsen it in patients already affected by it, due to reducing bone density. As a result of this, broken bones may be more likely. Ensure that you talk about the risks of this with your doctor before starting treatment.

Use of this medicine might make a blood clot or stroke more likely. If you notice symptoms of this, seek treatment immediately.

Seek immediate emergency medical attention if you suffer an allergic reaction. Symptoms to watch for, which may be indicative of a reaction, include skin rashes, hives, swelling of the face or limbs, trouble breathing, and trouble swallowing.

Always use Anabrez (Anastrozole) as you have been prescribed by your doctor. Never self-medicate or change your dosage without first consulting your doctor. The correct dosage can vary depending on your health, medical history, and the severity of the condition being treated.

This medication may not be safe for all patients. Before you begin using it always disclose the following to your doctor:

• If you are pregnant or breastfeeding.
• If you suffer from any allergies.
• If you suffer from any other health conditions or illnesses.
• If you are using any other medicine (including all non-prescription).
• If you are using any supplements, vitamins, or herbal products of any kind.