Curam Duo

Uses
Curam Duo (Amoxicillin/Clavulanic Acid) is a combination antibiotic treatment which works by killing bacteria. Amoxicillin is a penicillin-class antibiotic that fights and attacks the micro organisms by directly targeting their ability to form the cell walls they require to survive. By damaging the bonds which help hold the cell wall in place, it causes damage to the cell walls, and resulting from this the bacteria are killed.

However, there are some types of bacteria which have developed a resistance to penicillin antibiotics. These micro-organisms produce defensive enzymes called beta lactamases, and these enzymes offer resistance to penicillins due to them breaking the structure of the antibiotics. To overcome this, clavulanic acid, (a type of beta lactamase inhibitor) is added to the medicine.

It works by inactivating certain beta lactamase enzymes which are often present in resistant bacteria, including the plasmid-mediated type of enzyme often responsible for antibiotic resistance. This means that the overall spectrum of antibacterial activity is greatly enhanced. Infections treated include respiratory tract infections (upper and lower), otitis media and other ear infections, cellulitis and other skin or soft tissue infections, urinary tract infections (cystitis), joint infections and others not listed here.

Dosage and Administration
Curam Duo (Amoxicillin/Clavulanic Acid) is provided as tablets, each of which contains 500mg of amoxicillin. The content of clavulanic acid for every tablet is 125mg. Your dosage schedule will be carefully calculated by the doctor in charge of treatment. Usually, adults will be instructed to take 1 tablet every 12 hours, however this may vary from patient to patient depending on how severe the symptoms are. Infections of a severe nature may require treatment with a different strength medicine. Your doctor may direct you to take the tablets just before eating or else with the first bite of food, as administering it on an empty stomach could result in stomach upset.

Side effects
Antibiotic treatment with Curam Duo (Amoxicillin/Clavulanic Acid) may lead to side effects, such as:

• Nausea
• Sleep problems
• Pruritis affecting the skin
• Diarrhoea which is mild in nature
• Slight uncomfortable feeling in the stomach

All reactions should be reported to your doctor. You will need to see your doctor right away if you are affected by bloody or extremely watery diarrhoea, agitated or otherwise abnormal behaviour, seizures, bruises, weak muscles or any other side effects not listed here.

Precautions
A serious medical condition affecting the bowel (colitis) can occur in rare cases. If you notice fever, severe stomach cramps and persistent diarrhoea during or after treatment, see your doctor straight away.

This antibiotic medication may affect blood test results. If you are undergoing any medical tests, ensure that you inform your doctor that you are currently taking this medicine.

Always use Curam Duo (Amoxicillin/Clavulanic Acid) as you have been prescribed by your doctor. Never self-medicate or change your dosage without first consulting your doctor. The correct dosage can vary depending on your health, medical history, and the severity of the condition being treated.

This medication may not be safe for all patients. Before you begin using it always disclose the following to your doctor:

• If you are pregnant or breastfeeding.
• If you suffer from any allergies.
• If you suffer from any other health conditions or illnesses.
• If you are using any other medicine (including all non-prescription).
• If you are using any supplements, vitamins, or herbal products of any kind.