Soranib

Uses
Soranib (Sorafenib) is used for liver cancer and renal cell carcinoma. Its mechanism of action involves disrupting the growth of cancer cells in the body. In some cases, it may also be used for a type of thyroid cancer (differentiated thyroid carcinoma). The active ingredient in this medicine is known as a kinase inhibitor. Enzymes in the body called kinases are what helps the cancerous cells to grow.

They also help to cause blood vessels to supply the tumour with blood by forming new blood vessels (angiogenesis), which helps with the proliferation of the cancerous cells. Medical studies have demonstrated that this medicine can inhibit both multiple intracellular kinases, as well as cell surface kinases. This affects the tumour cells from growing and also stops blood vessels from reaching them. Patients with hepatocellular carcinoma (HCC or liver cancer) which is inoperable may be treated with this medicine, as well as those with advanced renal cell carcinoma.

Dosage and Administration
Soranib (Sorafenib) tablets each contain 200mg of the active ingredient. Your doctor will provide you with all details related to the correct dosage, as well as when to take it. Adult patients are normally told by their doctor to take 400mg (equal to 2 tablets) twice per day. It is normally given either 1 hour prior to eating or else 2 hours after a meal. In general, doctors advise patients to continue treatment until it stops providing the patient with clinical benefits. The doctor may also decide to withdraw treatment if a severe level of toxicity occurs.

Side effects
Side effects which may be caused by treatment with Soranib (Sorafenib) can include:

• Hair loss
• Tiredness
• Dry or red skin
• A decrease in weight
• Vomiting and pain in the stomach

Your doctor must be kept informed of all side effects that occur during the course of treatment. Immediate medical care will be needed should you suffer from any reactions of a serious nature, such as sores in the mouth, visual disturbances, increased perspiration, blisters on the feet or hands, discoloured urine or any others not mentioned here.

Precautions
This medication could cause damage to a baby if taken during pregnancy.

Severe bleeding or heart problems may occur in some patients treated with this medicine. See your doctor straight away if this happens.

Seek immediate emergency medical attention if you suffer an allergic reaction. Symptoms to watch for, which may be indicative of a reaction, include skin rashes, hives, swelling of the face or limbs, trouble breathing, and trouble swallowing.

Always use Soranib (Sorafenib) as you have been prescribed by your doctor. Never self-medicate or change your dosage without first consulting your doctor. The correct dosage can vary depending on your health, medical history, and the severity of the condition being treated.

This medication may not be safe for all patients. Before you begin using it always disclose the following to your doctor:

• If you are pregnant or breastfeeding.
• If you suffer from any allergies.
• If you suffer from any other health conditions or illnesses.
• If you are using any other medicine (including all non-prescription).
• If you are using any supplements, vitamins, or herbal products of any kind.