Xarelto

Uses
Xarelto (Rivaroxaban) is used to lessen the risk of a stroke in patients suffering from atrial fibrillation. It is an anticoagulant which works by preventing blood clots from being formed. Other indications include the treatment or prevention of DVT (deep vein thrombosis) and pulmonary embolism. This medicine is a direct factor Xa (FXa) inhibitor, meaning that it inhibits the activity of factor X and prothrombinase, the enzymes which play a vital role in the formation of blood clots.

This helps to reduce the formation of thrombin, a protease that can cause blood clots. As a result of this, it is able to indirectly block platelet aggregation (the process in which blood platelets clump together, which can result in a blood clot) caused by thrombin. In some cases, patients who have undergone knee or hip replacement surgery may be considered at risk of blood clots occurring in the lungs or legs. They may be directed to take this medicine so as to lower the risk of this occurring.

Dosage and Administration
Xarelto (Rivaroxaban) is provided as 10mg strength tablets which may be administered without regard to meals. Your doctor will carefully determine the dosage regimen based on your individual factors. Patients being treated for prophylaxis (prevention) of DHT following hip or knee replacement surgery are generally directed to take 10mg (one tablet) per day. If the patient has undergone a knee replacement, treatment may be required to continue for 12 days, however, those who have had their hip replaced may be directed to take it for 35 days. It is very important to note that this may differ in some cases and it will be necessary to closely follow the directions of the doctor in charge of treatment.

Side effects
Patients may notice side effects during the course of treatment with Xarelto (Rivaroxaban) tablets. Possible examples may include:

• Headaches
• Itchy feeling
• Mild bruising
• Dizzy sensation
• Sore muscles or limbs

In addition to the reactions listed above, patients may suffer from other side effects. If you are affected by bleeding that does not stop, nosebleeds that occur frequently, discoloured urine, blurred or otherwise unclear eyesight, feeling as if you may lose consciousness or any other serious side effects, ensure that you get medical help immediately.

Precautions
If you notice any symptoms of bleeding, go and tell your doctor. Get medical attention straight away if you suffer from any injuries, as the risk of bleeding will be higher than normal while this medicine is being taken.

Ensure that you notify any doctor or medical professional who is treating you that you are currently taking this medicine.

Seek immediate emergency medical attention if you suffer an allergic reaction. Symptoms to watch for, which may be indicative of a reaction, include skin rashes, hives, swelling of the face or limbs, trouble breathing, and trouble swallowing.

Always use Xarelto (Rivaroxaban) as you have been prescribed by your doctor. Never self-medicate or change your dosage without first consulting your doctor. The correct dosage can vary depending on your health, medical history, and the severity of the condition being treated.

This medication may not be safe for all patients. Before you begin using it always disclose the following to your doctor:

• If you are pregnant or breastfeeding.
• If you suffer from any allergies.
• If you suffer from any other health conditions or illnesses.
• If you are using any other medicine (including all non-prescription).
• If you are using any supplements, vitamins, or herbal products of any kind.