Tofranil

Uses
Tofranil (Imipramine) is used for alleviating depression, and experts believe that it works by inhibiting the uptake of noradrenaline, which helps to boost the mood and relieve depression. The active ingredient is a tricyclic antidepressant which is said to be derived from dibenzazepines (a type of chemical compound). By affecting serotonin and noradrenaline uptake (both of which are neurotransmitters), it can help to increase adrenergic synapses.

This in turn can lengthen the effects of these neurotransmitters on the mood after they are released. Another indication for this medication is bedwetting (referred to medically as enuresis). Medical experts are not entirely sure of how it achieves its therapeutic effects when used for this condition, however it has been theorized that its antidepressant action could be a contributory factor in controlling this condition.

Other doctors have stated that it may act on the cholinergic receptors, thereby helping to prevent bladder contractions and improve the patient's control over urination. Medical research has taken place, which focused on its effects if used to treat depression in alcoholics, depressive symptoms in patients with OCD and anxiety.

Dosage and Administration
Tofranil (Imipramine) coated tablets each contain 10mg of the active component. Adults treating depression are sometimes told by their doctor to commence treatment with 25mg, taken 1 to 3 times per day. This may be gradually increased by the doctor to a dosage ranging from 150mg to 200mg per day. After this, careful reduction of the dosage may be recommended if control of symptoms occurs, and the usual maintenance dosage is between 50mg and 100mg per day.

Elderly patients may be told to begin with 10mg per day, and the doctor may adjust this dosage, and instruct the patient to take 30mg to 50mg per day. Never exceed the dosage that your doctor prescribed during treatment. In general, full therapeutic effects in the treatment of depression will be noticeable 1 to 3 weeks after the commencement of treatment.

Side effects
Administration of Tofranil (Imipramine) has resulted in some patients experiencing side effects, including:

• Feeling drowsy
• Dilation of pupils
• Erectile dysfunction
• Dermatological photosensitivity
• Breast swelling affecting both men and women

Other reactions may also occur. Ensure that your doctor is notified of any side effects you experience. In rare cases, serious reactions may affect patients, and this will necessitate immediate medical care. Examples of this can include visual alterations, abnormal behavioural changes, spasms of the muscles, testicular swelling, tremors and other reactions that have not been listed here.

Precautions
The risk of heatstroke while exercising is increased while taking this medicine, and patients must take all the necessary precautions to ensure that this does not occur.

Dry eyes may occur during treatment with this medicine, and this could affect patients who wear contact lenses. Ask your doctor about this before commencing treatment.

Seek immediate emergency medical attention if you suffer an allergic reaction. Symptoms to watch for, which may be indicative of a reaction, include skin rashes, hives, swelling of the face or limbs, trouble breathing, and trouble swallowing.

Always use Tofranil (Imipramine) as you have been prescribed by your doctor. Never self-medicate or change your dosage without first consulting your doctor. The correct dosage can vary depending on your health, medical history, and the severity of the condition being treated.

This medication may not be safe for all patients. Before you begin using it always disclose the following to your doctor:

• If you are pregnant or breastfeeding.
• If you suffer from any allergies.
• If you suffer from any other health conditions or illnesses.
• If you are using any other medicine (including all non-prescription).
• If you are using any supplements, vitamins, or herbal products of any kind.