Amitrip-50

Uses
Amitrip (Amitriptyline Hydrochloride) is a TCA (an abbreviation for tricyclic antidepressant). Medicines belonging to this class of drugs are sometimes referred to as first generation antidepressants, and may cause more side effects than SSRIs (serotonin reuptake inhibitors) and other second generation antidepressant medicines. This drug's mechanism of action involves acting on the brain's nerve cells and increasing the amounts of serotonin and noradrenaline. As these chemicals can affect the mood, restoring their balance may help to relieve depression. In addition to being used for depression, obsessive compulsive disorder (OCD) and eating disorders, this medicine has also been used for a variety of other conditions.

Patients with fibromyalgia have taken it to reduce muscle spasms and improve sleep, and it has also been taken for neck pain or other type of chronic pain or nerve pain. It has even been taken to help prevent migraine. Another completely different use is treating bedwetting (nocturnal enuresis). It may help to prevent this by blocking the muscarinic receptors in the bladder, thereby helping to prevent nighttime urination. Medical studies have been conducted to determine its effects if used for tinnitus, irritable bowel syndrome and cyclic vomiting syndrome.

Dosage and Administration
Amitrip (Amitriptyline Hydrochloride) is supplied in 50mg strength tablets, which are administered orally. The correct dosage can vary greatly from patient to patient, based on factors such as the condition needing treatment and the patient's health. In all cases, the correct dosage will be determined by a doctor who will take into account the patient's individual circumstances. In some cases, adults treating depression have been told to start out with a dosage ranging from 25mg to 100mg (taken as 3 to 4 doses) or else a dosage of 50mg to 100mg taken before bed. Adjustments may be made by the doctor providing treatment when the maintenance dose is being determined.

The dosage for pain may vary, and some adult patients have been instructed by their doctor to take 75mg per day, either as a single dose or else as divided doses. If the doctor deems it necessary, the dosage may be adjusted. Patients may need to have their heart rate monitored, as well as regular blood pressure and ECG checks. In all cases, you must strictly adhere to the instructions given and only take the amount of medicine that your doctor tells you to take.

Side effects
Tricyclic antidepressants such as Amitrip (Amitriptyline Hydrochloride) can cause side effects, and a list of some examples is given here:

• Dry mouth
• Sleepiness
• A reduction in libido
• Appetite or body weight changes
• Swelling of the breasts affecting male or female patients

Remain in regular contact with your doctor during treatment, and report all side effects. Some of the reactions associated with this drug may be significantly more serious, and will require immediate medical care. Examples include hallucinations, tremors, muscular spasms, speech problems, unusual bruising or any other serious side effects that have not been listed here.

Precautions
If you abruptly stop taking this medicine, it is quite possible that unpleasant withdrawal symptoms may occur, including nausea, headaches and sleep difficulties. Your doctor may tell you to gradually reduce your dosage over a period of time in order to minimise the risk of this occurring.

Taking antidepressant medicines may help to prevent symptoms in some patients, however there is also the possibility that an increased risk of suicidal ideations or a worsening of depression may occur. It is necessary to discuss all of the possible risks of treatment with your doctor prior to the commencement of treatment. Tell your doctor immediately if you notice any behavioural changes after taking this medicine.

Seek immediate emergency medical attention if you suffer an allergic reaction. Symptoms to watch for, which may be indicative of a reaction, include skin rashes, hives, swelling of the face or limbs, trouble breathing, and trouble swallowing.

Always use Amitrip (Amitriptyline Hydrochloride) as you have been prescribed by your doctor. Never self-medicate or change your dosage without first consulting your doctor. The correct dosage can vary depending on your health, medical history, and the severity of the condition being treated.

This medication may not be safe for all patients. Before you begin using it always disclose the following to your doctor:

• If you are pregnant or breastfeeding.
• If you suffer from any allergies.
• If you suffer from any other health conditions or illnesses.
• If you are using any other medicine (including all non-prescription).
• If you are using any supplements, vitamins, or herbal products of any kind.