Premarin

Uses
Premarin (Conjugated Estrogen) is indicated for menopausal symptoms and the prevention of osteoporosis due to the menopause. Women suffering from medical disorders in which the amount of oestrogen in the body is lacking may also be treated with this medicine. In some cases, it has been used for treating certain types of cancer in men or women. These tablets are produced using a mixture of various oestrogens which have been obtained using natural sources. Oestrogen is an important female sex hormone which plays a vital role in the female reproductive system.

It also contributes to secondary sexual characteristics. During the menstrual cycle, it is secreted by the ovaries. However, as the menopause approaches, the production of oestrogen gradually slows down, leading to a decline in the amount circulating in the body. This can produce unpleasant symptoms, which may include vaginal dryness, itchiness, hot flushes and other symptoms. In order to alleviate these symptoms, your doctor may recommend hormone replacement therapy (HRT) with this medicine, which works by acting as a supplement to the body`s oestrogen levels.

Dosage and Administration
Premarin (Conjugated Estrogen) is provided as 0.625mg strength tablets which need to be administered in accordance with the dosing schedule that your doctor determines for you. It is possible for patients to administer the medicine without regard to meals. The dosage will differ depending on the condition for which it is being administered. Usually, if vaginal atrophy is being treated, your doctor will direct you to start out with the lowest possible effective dose (usually 0.3mg).

If this is the case, lower strength tablets will be needed. The doctor may decide to adjust the daily dosage based on how the patient responds to treatment. Women treating hypoestrogenism may be told to take 0.3mg or else 0.625mg per day, given on a cyclic basis (this means that it is taken for 3 weeks followed by a 1 week off period). Always follow the instructions given by your doctor.

Side effects
Treatment with Premarin (Conjugated Estrogen) might result in some side effects:

• Headaches
• Loss of hair
• Soreness in the breasts
• Unusual vaginal bleeding
• Pain and a bloated feeling in the stomach

You must make sure that your doctor is informed if any side effects are experienced during treatment. You will require immediate medical assistance and treatment if you are affected by depression, memory problems, lumps on the breasts, inflammation of the limbs, nausea and vomiting which is persistent or any other serious side effects that have not been listed here.

Precautions
Studies have shown that oestrogen alone hormone replacement therapy may cause an increased risk of deep vein thrombosis or a stroke.

During the course of treatment, your doctor may schedule breast examinations to check for breast cancer. It is important that you keep all appointments made by your doctor.

Seek immediate emergency medical attention if you suffer an allergic reaction. Symptoms to watch for, which may be indicative of a reaction, include skin rashes, hives, swelling of the face or limbs, trouble breathing, and trouble swallowing.

Always use Premarin (Conjugated Estrogen) as you have been prescribed by your doctor. Never self-medicate or change your dosage without first consulting your doctor. The correct dosage can vary depending on your health, medical history, and the severity of the condition being treated.

This medication may not be safe for all patients. Before you begin using it always disclose the following to your doctor:

• If you are pregnant or breastfeeding.
• If you suffer from any allergies.
• If you suffer from any other health conditions or illnesses.
• If you are using any other medicine (including all non-prescription).
• If you are using any supplements, vitamins, or herbal products of any kind.