Glivec

The information on this product's packaging is Turkish language only.

Uses
Glivec (Imatinib Mesylate) belongs to a group of drugs referred to as protein tyrosine kinase inhibitors. It is an anti-cancer medication primarily used as a treatment for leukaemia, however, it may also be used to treat other types of rare cancer, such as GIST (gastrointestinal stromal tumours) and DFSP (dermatofibrosarcoma). This medicine works by inhibiting the action of the abnormal protein (called c-kit) that causes the multiplication and growth of the cancer cells, thereby preventing the spread of the cancer.

Dosage and Administration
Patients undergoing treatment with Glivec (Imatinib Mesylate) must follow the dosage regimen prescribed by their doctor. The tablets are taken with a meal and a full glass of water. Adults treating leukaemia are generally told to take a dose of 400mg or 600mg, once per day. However, patients who have been directed to take 800mg per day are normally instructed to take it as two 400mg doses. In all cases, patients will be told by their doctor how long they need to continue treatment for. Other conditions may require different dosage regimens, and it is essential that all patients strictly follow the instructions provided by their doctor.

Side effects
Patients taking Glivec (Imatinib Mesylate) tablets may experience unwanted side effects, such as:

• Sinus pain
• Loss of weight
• Teary, watery eyes
• Reduced desire to eat
• Muscle cramps or pain affecting the joints

While you are being treated with this medicine, it is important to tell your doctor about any side effects which you experience. In rare cases, severe reactions are possible. See your doctor immediately if you notice bloody stools, weight gain, urinating more than usual at night, coughing up blood or bleeding of the eye. Remember that in addition to the side effects listed here, other reactions (which also require immediate medical care) may occur. Ask your doctor for more details.

Precautions
It is essential for the patient to inform the prescribing doctor if there is any history of hypertension, heart problems, diabetes, lung disease, medical conditions related to the thyroid or any illnesses involving the liver.

This drug should never be taken by pregnant women. During the course of treatment, all the necessary precautions should be taken to ensure that a pregnancy does not occur (such as using effective birth control or avoiding sexual intercourse). If you become pregnant while taking this medicine, consult your doctor immediately.

Seek immediate emergency medical attention if you suffer an allergic reaction. Symptoms to watch for, which may be indicative of a reaction, include skin rashes, hives, swelling of the face or limbs, trouble breathing, and trouble swallowing.

Always use Glivec (Imatinib Mesylate) as you have been prescribed by your doctor. Never self-medicate or change your dosage without first consulting your doctor. The correct dosage can vary depending on your health, medical history, and the severity of the condition being treated.

This medication may not be safe for all patients. Before you begin using it always disclose the following to your doctor:

• If you are pregnant or breastfeeding.
• If you suffer from any allergies.
• If you suffer from any other health conditions or illnesses.
• If you are using any other medicine (including all non-prescription).
• If you are using any supplements, vitamins, or herbal products of any kind.