Glivec

The information on this product's packaging is Turkish language only.

Uses
Glivec (Imatinib Mesylate) is a drug which is prescribed to treat leukaemia and certain cancers affecting the stomach. More specifically, it can treat a type of cancer called Philadelphia chromosome positive chronic myeloid leukaemia, as well as Philadelphia chromosome positive acute lymphoblastic leukaemia. Other conditions treated include hypereosinophillic syndrome, chronic eosinophilic leukaemia, dermatofibrosarcoma protuberans and gastrointestinal stromal tumours. This drug works by interfering with the growth of the cancer cells.

Dosage and Administration
The exact dosage required for patients taking Glivec (Imatinib Mesylate) can vary, depending on the type of cancer being treated. This medicine comes in the form of tablets, which are taken with food and a glass of water. Treatment of unresectable/metastatic, malignant gastrointestinal stromal tumours may require a dose of 400mg per day. If signs of disease progression are noticed, the patient may have their dose increased, and a dose of up to 800mg per day may be prescribed (administered as two 400mg doses). Other conditions, such as leukaemia, may require different doses, and it is essential that all patients strictly adhere to the dosage regimen prescribed by their doctor.

Side effects
Glivec (Imatinib Mesylate) may cause:

• Anxiety
• Appetite loss
• Watering of the eyes
• Sore muscles or joints
• Nasal congestion or pain affecting the sinus

Inform your doctor of any side effects you experience. You must seek immediate medical attention if you notice bloody stools, macular oedema, hearing problems, urinating more than you normally would, weight gain or any other signs of a serious reaction.

Precautions
Your doctor may tell you to regularly weigh yourself, so as to ensure that no rapid changes in weight may occur. In some cases, fluid retention causing weight gain may occur. Medical treatment will be required if this occurs.

Under no circumstances should this medicine be taken by pregnant women. Contraception should be used to ensure that a pregnancy does not occur.

Seek immediate emergency medical attention if you suffer an allergic reaction. Symptoms to watch for, which may be indicative of a reaction, include skin rashes, hives, swelling of the face or limbs, trouble breathing, and trouble swallowing.

Always use Glivec (Imatinib Mesylate) as you have been prescribed by your doctor. Never self-medicate or change your dosage without first consulting your doctor. The correct dosage can vary depending on your health, medical history, and the severity of the condition being treated.

This medication may not be safe for all patients. Before you begin using it always disclose the following to your doctor:

• If you are pregnant or breastfeeding.
• If you suffer from any allergies.
• If you suffer from any other health conditions or illnesses.
• If you are using any other medicine (including all non-prescription).
• If you are using any supplements, vitamins, or herbal products of any kind.