Progynova

Uses
Progynova (Estradiol Valerate) (formerly spelled as oestradiol valerate) is indicated for the treatment of the menopause. It is an oestrogen hormone that works by supplementing the body`s hormonal levels, which can be decreased due to the menopause. This form of treatment is called hormone replacement therapy (commonly abbreviated to HRT), and is generally used on a short term basis to relive vaginal burning, dryness and itching caused by the menopause.

Other menopausal symptoms it relieves include mood changes, sleep problems, hot flashes, night sweats and mucocutaneous involution. These distressing symptoms are triggered due to the progressive decline of oestradiol production by the ovaries, which is a primary characteristic of the menopause. The active ingredient in this product is an ester of oestrogen, which can reverse these menopausal symptoms by replenishing the body`s hormones. It may even slow down bone loss caused by the menopause, however it is not used as a first line treatment for osteoporosis.

In women who have not had a hysterectomy, it may cause excessive growth of the uterine lining (in the womb). Doctors may recommend the use of a progestogen so as to prevent endometrial growth (which could lead to endometrial cancer if left untreated). Use of a progestogen in combination with oestrogen replacement (referred to as combined HRT) has yet to be proven to interfere with the ability of oestrogen to work as indicated. Ask your doctor for more details.

Dosage and Administration
HRT with Progynova (Estradiol Valerate) is only on a short term basis. The need for treatment will be continuously re-assessed by your doctor, and it should only be continued in cases where the long term positive effects outweigh all potential risks of prolonged treatment. This medicine is provided as two blister pack strips, each of which contains 28 tablets.

Each strip contains 28 tablets, and has a calendar with the days printed on them printed on them, so as to make it easy for patients to know when each dose is due. Doctors generally tell patients to take one tablet (which contains 2mg of the active ingredient) every day. Although it does not matter if it is taken with or without food, doctors generally recommend taking it at the same time every day.

Side effects
Possible side effects which are associated with Progynova (Estradiol Valerate) include:

• Acne
• Weight gain
• Hair loss on the scalp
• Sore breasts or breast enlargement
• Spotting and unusual vaginal bleeding

The list of side effects provide above is not comprehensive, and other reactions are also possible. Certain reactions will require immediate cessation of treatment and immediate medical care. Examples include migraine (especially if you have no history of migraine), phlebitis, visual problems, hearing disturbances, inflammation of the limbs as well as other possible reactions that are not listed here.

Precautions
This medicine does not inhibit ovulation and it is not a contraceptive pill.

These tablets are only for use in women. If taken by male patients, transgender effects or other reactions could occur.

Seek immediate emergency medical attention if you suffer an allergic reaction. Symptoms to watch for, which may be indicative of a reaction, include skin rashes, hives, swelling of the face or limbs, trouble breathing, and trouble swallowing.

Always use Progynova (Estradiol Valerate) as you have been prescribed by your doctor. Never self-medicate or change your dosage without first consulting your doctor. The correct dosage can vary depending on your health, medical history, and the severity of the condition being treated.

This medication may not be safe for all patients. Before you begin using it always disclose the following to your doctor:

• If you are pregnant or breastfeeding.
• If you suffer from any allergies.
• If you suffer from any other health conditions or illnesses.
• If you are using any other medicine (including all non-prescription).
• If you are using any supplements, vitamins, or herbal products of any kind.