Sinemet

Uses
Sinemet (Carbidopa/Levodopa) is indicated for the treatment of Parkinson's disease and DRD (dopamine-responsive dystonia). The brain converts levodopa (one of the ingredients in this medicine) into dopamine, which acts as a replacement for the low dopamine levels which are often present in patients with Parkinson's disease.

Dopamine is considered to be important in helping to control bodily movement, and increasing the amount of it in the brain helps to reduce or control stiffness, shaking and movement difficulties. Carbidopa helps to lessen the occurrence of vomiting and nausea, which is a common side effect of levodopa. It can also make it easier for the prescribing doctor to adjust the dosage, so as to achieve optimum results.

Dosage and Administration
Sinemet (Carbidopa/Levodopa) tablets each contain 250mg of levodopa, whereas the carbidopa content is 25mg. Patients who are already undergoing treatment with levodopa must cease taking it at least 12 hours before commencing treatment with this combination drug. If the patient has been taking a dosage of levodopa in excess of 1500mg per day, there is a possibility that the doctor will instruct them to take one tablet 3 to 4 times per day. Further adjustments, such as for maintenance therapy, will be made by the doctor based on the patient's response to therapy, and close monitoring of the patient will be required.

Side effects
Treatment of Parkinson's disease with Sinemet (Carbidopa/Levodopa) might result in side effects, such as:

• Insomnia
• Flatulence
• Blurred vision
• Muscular pain
• Weight loss or gain

It is important to regularly visit your doctor as scheduled, and report any side effects that occur. Although less common, serious side effects are also possible. If you experience signs of dyskinesia, hallucinations, pain when urinating, urinary retention, priapism or any other serious side effects which have not been listed here.

Precautions
If you experience gambling urges while taking this medicine, tell your doctor as soon as possible.

Patients affected by narrow angle glaucoma must tell their doctor about their condition before starting treatment with this drug.

Seek immediate emergency medical attention if you suffer an allergic reaction. Symptoms to watch for, which may be indicative of a reaction, include skin rashes, hives, swelling of the face or limbs, trouble breathing, and trouble swallowing.

Always use Sinemet (Carbidopa/Levodopa) as you have been prescribed by your doctor. Never self-medicate or change your dosage without first consulting your doctor. The correct dosage can vary depending on your health, medical history, and the severity of the condition being treated.

This medication may not be safe for all patients. Before you begin using it always disclose the following to your doctor:

• If you are pregnant or breastfeeding.
• If you suffer from any allergies.
• If you suffer from any other health conditions or illnesses.
• If you are using any other medicine (including all non-prescription).
• If you are using any supplements, vitamins, or herbal products of any kind.